Sitting places more pressure on a disc vs. standing. Standing up and moving at least every hour on the hour is best not only for the spine, but also increases brain activity and increases energy levels. Read More
Struggle to get up every hour, just try drinking a full glass of water every hour or two, and that should force you to get up. Having a variable desk to allow for sitting to standing is always best for an office, then you have the option of doing either one. Arizona state university ran a study in which they studied the effects of sitting only vs. sitting and taking walk breaks periodically. They found that all thinking skills, memory, and decision making tests studied significantly improved when the participants were allowed to get up and move.
https://www.nytimes.com/2017/10/26/well/move/thinking-brain-exercise.html
